The Florida Highway Patrol is investigating a crash that happened on northbound I-75 at mile marker 135 at midnight into Sunday.
Troopers said a 24-year-old Port Charlotte man was heading north on I-75, toward Colonial Boulevard. Driving in front of him was a van with kids inside.
FHP said the Port Charlotte driver hit the rear end of that van, in the crash.
The van came to a rest on the grass, off the highway. A 4-year-old girl inside the van has critical injuries. She is in the hospital, FHP reports.
There is no word on charges, yet.